The basic study of antithrombotic effect of newly-synthetised drug LK732 has been immediately used by Slovenian pharmaceutical industry. The results of study of some protective drugs (some established and some new calcium antagonists, sex hormones, other drugs) on isolated hearts and isolated vessels are important for clinical use and in development of new drugs in Slovenia and the other world. Slovenia could economically benefit from our cooperation with foreign partners in this field. Our discovery of pharmacological and hypoxic preconditioning of the vessels as the possible vascular protection from hypoxia/reoxigenation will be used in clinical medicine as prevention and treatment of some vascular dieseases in Slovenia as well as in the world. The studies of action of endothelins in hypoxia and of mechanisms of action of some components of honey-bee venom will help in prevention of some vascular deseases, especially atherosclerosis, and in development of drugs for their treatment. The newly-synthetised peptide penetrating the cell membranes, also contracts the isolated porcine and human vessels. These results have been registered as a patent together with a Slovenian (prof. M. Zorko) and a Swedesh (prof. U. Langel) research group. The results of experiments on isolated stomach and atrium are important for pharmacodynamic testing of drugs with inhibitory effects on stomach secretion (used in treatment of stomach ulcer) in pharmaceutical industry (also in Slovenia). The updating of equipment for studying the secretion in the isolated part of stomach and the development of respective software enables a more reliable determination of action parameters of different drugs influencing the stomach secretion. The results of our studies on antipsychotics and antihistaminics show that the "side effects" of antidepressants may be used in clinical set up. At the same time they are supplementing the studies from other laboratories. A long lasting planning and the development of new pharmacological methods is necessary for the development of new drugs. Much of know-how used in our current research is obtainable in Slovenia only at our Institute. In the research work acquired knowledge is transfered to students of pharmacy, medicine and dental medicine, and biology. The knowledge and the people will also be absolutely necessary for the new Medical faculty in Maribor where there are no adequate possibilities in this field. The results of our research work are aplicable in pharmacology, clinical pharmacology, pharmaceutical industry and enable Slovenia to parallel the world development in the field of pharmacology.