Systems biology approaches being applied to animal breeding represent an opportunity to derive greater benefits from animal production systems. The increasingly detailed investigations in systems biology have led to a large amount of data dispersed over various sources; therefore, a centralized knowledge base is in demand. In this study, we have integrated cattle genomics data of heterogeneous sources and types and developed a bioinformatics tool to study genotype-phenotype associations in cattle.
COBISS.SI-ID: 3622280
Single nucleotide polymorphisms (SNPs) located in microRNA (miRNA) genes (miR-SNPs) have attracted increasing attention in recent years due to their involvement in the development of various types of cancer. Therefore, a systematic review on this topic was needed. Our study showed that, despite a large number of variations currently known to be located within miRNA genes in humans, most of them have not yet been tested for association with cancer.
COBISS.SI-ID: 3609992
It has been shown that miRNA polymorphisms are linked with important plant traits for agricultural production. Genetic variability of plant miRNA genes has been systematically studied only in rice. In this study we used the upgraded online tool miRNA SNiPer which now enables analysis of 22 genomes, including seven plant species.
COBISS.SI-ID: 3663752