The paper proposes a fully automatic pre-processing scheme for real-time registration of the breast dynamic contrast-enhanced magnetic resonance images (DCE-MRIs). It consists of an intensity inhomogeneity correction followed by a breast region of interest segmentation. To correct the intensity inhomogeneity in the breast images, a combination of a greyscale morphological closing with the Gaussian filtering is used. The breast region of interest segmentation is based on fitting the human chest by an ellipse. The main advantages of the proposed pre-processing scheme are a low computational complexity and robustness to the breast density. The scheme was evaluated on 50 T1-weighted DCE-MRIs demonstrating a significant decrease in the time taken for registration (almost a factor 2 for the affine registration and almost a factor 9 for a non-linear B-spline free-form deformation).
COBISS.SI-ID: 28304935
In this paper, a new method for Multi-parametric analysis of MR images is presented. Maps of relaxation time T2 and of the apparent diffusion constant (ADC) were used to calculate a two-dimensional histogram in which each point has two coordinates. These are T2 and ADC, while the point value is presented by brightness which is proportional to the number of points in the analyzed images having a pair of values of T2 and ADC. The usefulness of such an analysis are presented in the analysis of blood clots. Using the presented method we can effectively distinguish between venous thrombi, acute and chronic pulmonary emboli and sedimented clots. The method of analysis is also useful for classification of other types of tissues. In this project, we will use it to distinguish between healthy and cancerous breast tissues.
COBISS.SI-ID: 28187943
Future potential scope of MR imaging is also dentistry. In this paper, we have shown that MRI can be effectively used to determine the impairment of the dental pulp due to caries. We have shown that in the affected parts of the dental pulp due to the inflammatory response the apparent diffusion constant is reduced. We also tried to determine the correlation between the change in the diffusion constant and international caries scale ICDAS. The used method is can be used also for the quantitative analysis of the inflammatory response of all other types of tissues.
COBISS.SI-ID: 1673595