Mirjam Frohlich gave an invited lecture at the 3rd Annual Meeting of World Academy of Cosmetic Surgery (WAOCS) in Vienna, Austria. She presented the potential of the use of cells derived from adipose tissue for the purposes of soft tissue regeneration. Among other things, she presented results from her studies, focusing on endothelial cells derived from adipose tissue for the vascularization purposes. At the conference she made contacts and initiated collaborations with partners for the development of new clinical product – cells from adipose tissue with a strong vascular potential. The active R&D collaboration with the well known cosmetic surgeon dr. Peter Lisborg (Klinike PKLP Ästhetic, Klagenfurt, Austria) is ongoing.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 27527463At the Meeting of the Society for In Vitro Biology 2013, she had a paper on alternative sources of human smooth muscle cells, which present an important component for engineering of functional vascular structures.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 27583783At the 4th International Congress Nanotechnologym Medicine, and Biology, she had a paper on the use of primary cells, including ASC, for purposes of safety testing of materials which are being developed for biomedical purposes. When testing biomaterials it is of crucial importance to choose the most relevant cell type – in most cases, well established vasculature of the tissue is a prerequisite for succesfull integration of a biomaterial, therefore it is important that the biomaterial doesn’t cause negative effects on vascular cells.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 16799510At the 25th European Conference on Biomaterials, ESB 2013 she had a paper on the use of primary cells for the purposes of safety testing of materials being developed for the purpuses of bone tissue regeneration. Well established vasculature is a prerequisite for successfull integration and regeneration of bone tissue, therefore the implanted material should support the survival and growth of vascular cells.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 27056423Results of the project have a great applicative value as they served as a basis for new cell technology platform and a product (set for isolation of regenerative cells from the adipose tissue). New cell technology platform is based on a cellular component with high vascular potential and is currently being used for two clinical indications: i) regeneration of maxilar bone tissue (5 patients so far), and ii) rejuvenation of facial tissues (7 patients so far). The results are encouraging. The new technology platform has a great potential also for other clinical indications, e.g. regeneration of muscle tissue. Based on the project results, a new Quality Control method can be developed, which would – on the prediction of vascular potential – further increase the success of new cell therapies.
F.09 Development of a new technological process or technology