After the invitation of the Editor-in-Chief of Current Organic Chemistry professor Atta-ur-Rahman, FRS, our previously published review on the unnatural alpha-amino acids synthesis [Perdih A. and Sollner Dolenc M. Curr Org. Chem. 2007, 11, 801-832] has been revised and updated into a new review article also discussing novel contributions in the field covering the period from 2007-2010. The newly published review presented and discussed selected synthetic methodologies leading to unnatural alpha-amino acids, including chiral catalysts that enable enantioselective synthesis and microwave-assisted synthesis. Solid phase synthesis and construction of organometallic alpha-amino acids revealed the wide scope of influence that this field has in organic chemistry. Additionally, the article was aimed to provide a brief insight into biosynthetic approaches to the synthesis of alpha-amino acid derivatives, thus giving an overall appreciation of the field. Several presented methods also provide access to interesting molecules that could act as potential antibacterial compounds.
COBISS.SI-ID: 3129713