In collaboration with partners from Romania we managed to synthesize multi-layered graphene structures perpendicular to the surface of cardiovascular implants which were stable upon incubation with human blood. The structures were tested thoroughly for their morphological properties and the activation of blood platelets was studied. The biological results confirmed the original hypothesis that the blood platelets do not activate on such nanostructured surfaces. The results were explained by minimization of the contact area between the implant and platelets. Several embodiments were elaborated and the corresponding patent application was filed.
F.09 Development of a new technological process or technology
COBISS.SI-ID: 28413223This topical conference attracted over 300 participants. Experts of different education presented recent results on curing cancer and cardiovascular diseases with nanoparticles as well as nanostructuring of materials likely to be contacted with biological cells and body liquids. The project leader was one of 3 plenary speakers.
B.04 Guest lecture
COBISS.SI-ID: 26948903The project leader gave a lecture at the Centre for plasma Medicine, University of Nagoya, Japan. He introduced extremely nonequilibrium gaseous plasma and interaction of plasma species with organic materials. He presented innovative technologies developed in his group in last few years protected by patents granted in various countries including Japan. He explained processing mechanisms suitable for application for sterilization of delicate materials, cleaning catheters and similar medical instruments as well as selective necrosis of cancer cells.
B.04 Guest lecture
COBISS.SI-ID: 26623783The head of the project was invited to give a lecture at Annual Joint Symposium & Exhibition Florida Chapter of American Vacuum Society (AVS). He presented numerous applications of such plasma with an emphasis on modern fields of interdisciplinary science including modification of cardiovascular implants for better biocompatibility.
B.04 Guest lecture
COBISS.SI-ID: 25780519Project leader served as the supervisor of a young researcher who prepared a comprehensive thesis on hemocompatibility of cardiovascular implants. The NH radicals were created in flowing afterglow of ammonia plasma and allowed to interact with polymer surface forming amino groups. These groups served as anchor sites for covalent bonding of heparin and thus excellent hemocompatibility.
D.09 Tutoring for postgraduate students
COBISS.SI-ID: 278286336