Before deciding if the HPV screening in males is scientifically and ethically justified, one must answer to the following questions: what sort of disease do we want research, in what sort of population and why ? Do the screening render the discovery of the disease earlier than without screening and do the screening enable better therapeutic approach, what's the better time interval for screening, etc... Considering the actual guidelines proposed by leading world scientific associations, the use of HPV testing in males is not recommended.
B.04 Guest lecture
COBISS.SI-ID: 1325484The prevalence of HPV DNA in genital and seminal samples of men from infertile couples was high. Also, wide range of different HPV types was detected. HPV DNA was present in the semen samples of more than 13% of men. Sperm quality between men with HPV DNA in semen and men, where HPV DNA was not detected, did not differ significantly. Tetravalent vaccine HPV types were detected in more than 10% of men with HPV DNA. Spermatozoa could be a possible vector of HPV transmission. Thus, female patients in uterine insemination cycles using donor semen could have been exposed to HPV. Since some negative impact of HPV on embryo fertilization and embryo development was observed, some authors suggest an inclusion of HPV screening for gamete donors before the ART procedure.
B.04 Guest lecture
COBISS.SI-ID: 1325740