P.I. of the project was a Guest Editor of the special issues of the Journal of Steroid Biochemistry and Molecular Biology, 2012, Vol. 129, entitled »Steroids and microorganisms« (COBISS.SI-ID 29395673) and a Guest Editior of a Special Issue of Chemico Biological Interactions 2013, Vol. 202, 1-3, entitled »Enzymology and Molecular Biology of Carbonyl Metabolism 16« (COBISS.SI-ID 30520281).
C.03 Guest-associated editor
The P.I. of the project was a member of the Program Organizing Committee of the Congress on Steroid Research, which took place between March 10 and 12, 2013 in Chicago USA She was also chair of the session #3 Reproduction and Menopause. (http://www.steroidresearchcongress.com/conference-committee.html). The P.I. of the project was a member of the Organizing Committee of the 17th International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism, which took place between July 8 and 13 in Pocono Mountains, USA.
B.01 Organiser of a scientific meeting
The patent WO 20137178794 A1 presents a new approach in noninvasive diagnostics of ovarian endometriosis by determining metabolites in blood of patients. The analytes were quantified by electrospray ionization tandem mass spectrometry and eight lipid metabolites and 81 ratios between individual metabolites were identified as endometriosis-associated biomarkers. A stepwise logistic regression procedure was used for selecting the best combination of biomarkers and for development of diagnostic algorithm. lnventors of this patent are from University of Ljubljana and Helmholtz Zentrum Munich.
F.32 International patent
COBISS.SI-ID: 299816571)»Grants4Targets Lecture, From Targets to Novel Drugs«, Bayer Health Care, Berlin, Germany 2010, 17ßHSDs in endometriosis . [COBISS.SI-ID 26705113]; 2) »15th World Congress on Advances in Oncology«, Loutraki, Greece, 2010, Estrogen-metabolizing enzymes in breast cancer cell lines[COBISS.SI-ID 27493337]; 3) »Symposium Molecular Medicine and Biotechnology«, Ljubljana, Slovenia 2012, Roles of steroid hormones in hormone dependent diseases [COBISS.SI-ID 29998297]; 4)»16th International Meeting on Enzymology and Molecular Biology of Carbonyl Metabolism«, Ploen, Germany, 2012, Domination of 17-ketosteroid reductase activity over aromatase activity in endometrial cancer [COBISS.SI-ID 30139865]; 5) »Wroclaw Seminar on Nuclear Receptors« Wroclaw Poland, 2012, Estrogen receptors in endometrial cancer and endometriosis [COBISS.SI-ID30125529 ]; 6) »Perelman School of Medicine at the University of Pennsylvania«, Phildelphia, USA, 2013, Estrogen metabolism and endometrial cancer (COBISS.SI-ID 30431449); 7) »Medical University of Vienna, Endometriosis Center«, Vienna, Austria, 2013, Noninvasive biomarkers of endometriosis : myth or reality (COBISS.SI-ID 30899417); 8) »Department of Gynecology, University Clinical Centre« Ljubljana, 2013, Estrogens and endometrial cancer (COBISS.SI-ID 30956505); 9) »Medical University of Vienna, Department of Pathophysiology«, Vienna, Austria 2014, Estrogen biosynthesis, phase I and phase II metabolism and estrogen action in endometrial cancer [COBISS.SI-ID31374041 ], 10) »2nd Austrian Biomarker Symposium«, Vienna, Austria 2014, Metabolites as diagnostic biomarkers of ovarian endometriosis [COBISS.SI-ID31374297 ]
B.04 Guest lecture
P.I. was supervisor or co-supervisor to six Ph.D. students: KOCBEK Vida. Study of potential biomarkers in ovarian endometriosis : 2013. [COBISS.SI-ID 782967] BERANIČ Nataša. Study of progesterone metabolism, role of aldo-keto reductases and progestins in endometriosis : 2013 [COBISS.SI-ID 266472448] HEVIR-KENE Neli. Studies on estrogen and progesterone metabolism in endometrial cancer and ovarian endometriosis : 2011 [COBISS.SI-ID 258770688] BROŽIČ Petra. Preparation of recombinant human hydroxysteroid dehydrogenases and study of their inhibitors : 2010 [COBISS.SI-ID 251130880] STARČEVIĆ Štefan. Design, synthesis and evaluation of new nonsteroidal inhibitors of 17ß-hydroxysteroid dehydrogenase type 1 : 2011 [COBISS.SI-ID 3030385] BRUNSKOLE ŠVEGELJ Mojca. Structure/function relationship of short-chain dehydrogenases/reductases and their inhibitors : 2011 [COBISS.SI-ID 256628736] P.I. was also co-supervisor to seven undergraduate students.
D.09 Tutoring for postgraduate students