In September 2011 4th BBBB-Bled International Conference on Pharmaceutical Sciences took place in Bled. One of its main topics were novelties in the field of drug delivery, including nanocomposites which are the main focus of our project. Conference visited 350 participants from 29 counties. Approximate share of foreign experts was 60%. Our research results were presented at the conference as three poster presentations and published abstracts (COBISS ID 3118961, 3119217, 3119473). Furthermore, prof. dr. Julijana Kristl was the conference president and assoc. prof. dr. Saša Baumgartner the conference general secretary, both playing key roles in conference organization and realization. The main goal of the conference was to enable and strengthen scientific cooperation home and abroad between academic researchers and experts in industry. The topics presented at the conference gave or indicated answers to some challenges in modern pharmaceutical development, however, many challenges were let unsolved, representing a driving force for further, even more intense development.
B.01 Organiser of a scientific meeting
In the diploma thesis the influence of various polymer solution (viscosity, conductivity, surface tension) and process (voltage, distance to collector, flow rate) parameters on formation of PVA/PEO nanofibers was systematically investigated. On the bases of obtained results it was concluded that no approcah is universally applicable to obtain smooth, beadless nanofibers, therefore process conditions should be individually optimized for each combination of polymer and solvent.
D.10 Educational activities
COBISS.SI-ID: 3056241In the diploma thesis an Erasmus student from University of Lisbon investigated solution parameters of chitosan and polyethylenoxide (PEO) blends with or without addition of surface active substance (triton X-100) and organic solvent (DMSO). Then optimal process parameters were chosen to enable formation of electrospun nanofibers and in the last part in vitro biocompatibility of nanofibers was tested using keratinocyte cell line. The results showed that environmental conditions (air flow and relative humidity) are besides solution parameters key factors affecting formation of beadless nanofibers. Ratio of polymers in nanofibers was shown to exert significant impact on their behavior upon contact with aqueous conditions. Formulated nanofibers enabled attachment of keratinocytes in vitro, however, the cell morphology was changed due to growth on nanofibrillar surface.
D.10 Educational activities
COBISS.SI-ID: 3198065