This paper describes the preparation and potential use of zinc phosphate nanoparticles with bound TNF-alpha analogues. TNF-alpha bound in such nanoparticles has reduced biological activity, but conserved epitopes, so such particles would be useful for active immunotherapy in chronic inflammatory diseases where TNF-alpha levels are significantly increased.
COBISS.SI-ID: 4607770
The chapter in the international publication describes the use of zinc phosphate in different biomedical applications, especially as implants and bone replacement materials, nucleic acid delivery, vaccine adjuvant and as a delivery system for different drugs.
COBISS.SI-ID: 4607771