Munc18-1 and Munc18-2 display distinct subcellular compartmentalization and can coordinate the insulin exocytotic process differently as a consequence of the actual [Ca2+]i.
COBISS.SI-ID: 512148536
The study demonstrates the importance of donor endothelial cells on the revascularization of the pancreatic islets after transplantation.
COBISS.SI-ID: 18639624
cAMP modulates Ca2+-dependent exocytosis in mouse beta cells mainly through a PKA-dependent mechanism by sensitizing the insulin releasing machinery to [Ca2+]i; Epac2 may contribute to enhance the rates of secretory vesicle fusion.
COBISS.SI-ID: 66514689