The "4D Biology Workshop for Health and Disease" aimed at finding the best organizing principles for large-scale proteomics, interactomics and structural genomics/biology initiatives, and setting the vision for future high-throughput research and large-scale data gathering in biological and medical science. The workshop provided a strong basis for creating major possibilities in advancing research and clinical applications towards personalized medicine.
COBISS.SI-ID: 4515866
EPR/FTIR characterization of the lipid membranes that facilitate ostreolysin binding showed that the average membrane fluidity of ostreolysin-susceptible liposomes alone cannot account for the membrane activity of the protein. EPR spectra strongly suggest that chemical properties of membrane constituents, their specific distribution, and physical characteristics of membrane nanodomains, resulting from the presence of sterol and sphingomyelin (or a highly ordered phospholipid, dipalmitoylphosphatidylcholine), are essential prerequisites for ostreolysin membrane binding and pore-formation.
COBISS.SI-ID: 2185551