We used CT perfusion to evaluate the acute and late effects of radiation therapy on spinal cord hemodynamics in patients without symptoms of myelopathy who have not been treated with radiotherapy, after receiving 40 Gy and 70 Gy of irradiation and )=4 months after radiotherapy. We found out that radiotherapy of the head and neck may cause transient perturbations of spinal cord perfusion that seem to reverse after treatment. There are no definite chronic effects of radiotherpy on spinal cord perfusion observable at the typical doses administered during treatment of head and neck malignancies.
COBISS.SI-ID: 947579
In this paper, therapeutic range of intraarterial chemotherapy in verrucous carcinoma of the head and neck is discussed and its effectiveness is compared to that of other established methods, i.e. surgery and conventional intravenous chemo(radio)therapy. In conclusion, due to proven effectiveness and low toxicity of intraarterial application of methotrexate it should be considered when designing new treatment protocols for patients with this type of cancer who are not candidates for surgery (with advanced disease or not fit for major surgical procedure).
COBISS.SI-ID: 832123
Image cytometric analysis of cell suspensions prepared from primary tumor tissue and fine needle aspiration biopsy cell samples of neck metastases from 21 patients with squamous cell carcinoma of the head and neck treated with concomitant chemoradiation was performed. A specific pattern of correlation between established prognostic indicators and nuclear features of samples from primary tumors and those from neck metastases was observed. In the present study, image cytometric nuclear features proved to be a promising candidate marker for recognition of biologically different tumor subgroups.
COBISS.SI-ID: 28182745
We present a novel use of sliding epiglottoplasty as an alternative method for closing mucosal defects in selected laryngectomies with partial pharyngectomy. Analysing series of 17 patients we concluded that if the oncological circumstances allow its preservation in laryngectomy with partial pharyngectomy, the epiglottis is an ideal structure for closing the defect. In comparison to other methods, the epiglottoplasty is a shorter procedure, requires a smaller surgical team, results in less trauma, has a lower incidence of complications, and enables faster recovery.
COBISS.SI-ID: 0000000
Lack of international acceptance of a uniform classification of neck dissections, prompted re-evaluation of neck dissection classifications, and suggestion of a new system of terminology. To avoid confusion, and misinterpretation among head and neck surgeons, we propose a new classification which is logical, simple, and easy to remember, and conveys precisely the extent of the lymphatic and non-lymphatic structures removed in a neck dissection.
COBISS.SI-ID: 1025403