Authors: LUNDER, Mojca, BRATKOVIČ, Tomaž, URLEB, Uroš, KREFT, Samo, ŠTRUKELJ, Borut Description: A novel method for elution of peptide ligands from bacteriophage display libraries was developed by means of ultrasound in order to obtain selective peptides, eluted from target proteins.
COBISS.SI-ID: 2347377
Authors: BRATKOVIČ, Tomaž, LUNDER, Mojca, URLEB, Uroš, ŠTRUKELJ, Borut. Description: By means of phage display, we succesfully isolated and characterized peptids that act as inhibitors of MurD and MurE enzymes in low micromolar concentration
COBISS.SI-ID: 2330225
Author: BRATKOVIČ, Tomaž Description: The article deals with the broad review of the field of phage display with the emphasis on pharmaceutical and medical biotechnology. Some of our results are included as well.
COBISS.SI-ID: 2755697
Authors: RAVNIKAR, Matjaž, ŠTRUKELJ, Borut, OBERMAJER, Nataša, LUNDER, Mojca, BERLEC, Aleš Destcripition: Chronic inflammatory diseases are one of the most devastating modern malformanties.Tthe main cause for imflammation is TNFalpha.In order to block te acitvity of TNFalpha, we develope the recombinant Lactoccocus lactis by means of phage display that expresses the hipervariability peptidic domain at the surface.
COBISS.SI-ID: 24011815
Authors: GASER, Dominik, ŠTRUKELJ, Borut, BRATKOVIČ, Tomaž, KREFT, Samo, PUNGERČAR, Jože, LUNDER, Mojca Descripition: Two target proteins: ammodytoxin C and phospoholipase A2 were bound and several peptides were isolated from bacteriphage random peptide library against both proteins. The result indicates that both enzymes might have structurally similar epitopes.
COBISS.SI-ID: 2656113