Unknown role of Epo and EpoR in cancerous tissue and lower survival of patients on rHuEpo therapy raised a question about the adequacy of rHuEpo treatment in cancer patients. Study include patients with metastatic breast cancer, planed to undergone chemotherapy and rHuEpo. Samples of blood, urine and fine needle biopsy will be taken during the study: before and after rHuEpo treatment. We will determine the level of serum Epo, analyze the global gene expression and transfer of the Epo signal, and attempt to elucidate the action of rHuEpo on cancerous cells on the molecular and cellular level.
D.01 Chairing over/coordinating (international and national) projects
COBISS.SI-ID: 1111111