Independant prognostic factors for disease-free survival in 228 patients with thyroid carcinoma were: tumor diameter larger than 6 mm and the presence of metatstases in cervical lymph nodes as shown by multivariate statistical analysis.This paper was included in the only till now published meta-analysis, which included all the 17 papers published until 2008, which included more than 35 patients.This paper was cited 6 times in magazines with impact factor in year 2010.
COBISS.SI-ID: 718715
In none of the 107 incidentally found microcarcinomas there were recurrence of the disease in the lymph nodes. In 147 patients with preoperatively proven microcarcinoma lymph node metastases were more common in men, those younger than 45 years and with follicular variant of papillary microcarcinoma than in women, older than 44 years and with the classic form of papillary microcarcinoma. These data are of practical importance, as they help in the decision about prophylactic lymphadenectomy.
COBISS.SI-ID: 724091
By multivariate logistic regression we found out taht predictive factors for thyroid cancer in 327 patients with thyroid follicular neoplasm were: tumor diameter >4 cm and thyroglobulin levels >300 ng / mL. This is the largest in the literature published series of patients with follicular neoplasm. Our finding that makes it possible through simple and inexpensive laboratory test to predict whether a patient has a carcinoma, and help to decide about the extent of surgical procedure. This enables reduction of the rate of unnecessary complications and repeated surgical procedures.
COBISS.SI-ID: 654459
In general, there is an opinion that thyroid Huerthe cell carcinoma does not accumulate radioiodine. We reported our experience in treating patients with this tumor with radioiodine in 2003 in the journal Thyroid and published a chapter in the above-mentioned book. Our arguments to treat patients with Herthle cell carcinoma with radioiodine have convinced professional circles, so our publication is cited in the treatment guidelines of the European Association of Nuclear Medicine (M. Luster et al. 2008).
COBISS.SI-ID: 788091
By multivariate logistic regression we found out that the predictive factors for thyroid cancer in 279 patients with Hürthle cell thyroid neoplasm were: age of patients >65 years and thyroglobulin levels >1000 ng/mL. Our finding that the concentration of thyroglobulin is a predictive factor makes it possible through simple and inexpensive laboratory test more accurately to predict whether a patient has a carcinoma or not, and it is easier to decide on the extent of surgical procedure. This enables reduction of the rate of unnecessary complications and repeated surgical procedures.
COBISS.SI-ID: 931707