The study was aimed at assessing the ability of tumor vaccine - CpG ODN class C in combination with irradiated melanoma tumor cells B16F1 to trigger the antitumor immunity in experimental tumor model in mice. A significant preventive antitumor immunity was achieved with the vaccine and two additional injections of CpG ODN. In more than 80% of survivors, a long-lasting immunity was triggered. The therapy with the vaccine and two additional injections of CpG ODN significantly prolonged survival of tumor bearing mice.
COBISS.SI-ID: 528507
The aims of our study were to find out if there is a difference in the appearance frequency of hTERT mRNA in plasma samples of early breast cancer patients, non-cancer patients and healthy individuals, and to determine whether surgical removal of the tumor affects the presence of hTERT mRNA in plasma of early breast cancer patients. We found statistically significant difference of hTERT mRNA presence in plasma of early breast cancer patients when compared to healthy individuals, and we found that hTERT mRNA in plasma of early breast cancer patients is affected by surgical removal of tumor.
COBISS.SI-ID: 674939