Aegerolysins, discovered in fungi, bacteria and plants, are highly similar proteins with interesting biological properties. Certain aegerolysins possess antitumoral, antiproliferative, and antibacterial activities and could be exploited in the prevention of atherosclerosis, or as vaccines. Besides, some aegerolysins could be used as specific markers for raft-like membrane domains. They are biochemically well characterized all-ß structured proteins sharing the following common features: low isoelectric points, similar molecular weights (15-17 kDa), and stability in a wide pH range.
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