We compared intima media thickness (IMT) and plaque occurrence in the carotid arteries in 104 nondiabetic patients (stages 1-5 of CKD) with those in 40 healthy control subjects. The IMT values (0.69 vs. 0.59 mm; P < 0.002) were higher in patients. More patients had plaques (46.2 vs. 17.5%; P < 0.002), and number of plaques was higher. Negative correlation between IMT, presence of plaques, their number, and Cr-EDTA clearance were found in patients. With multiple regression analysis, relationship between IMT and Cr-EDTA clearance and presence of hypertension was found.
COBISS.SI-ID: 2891327
361 patients with ischemic stroke and glomerular filtration rate (GFR) < 90 ml/min/1.73m2 were followed-up. There were 49 in-hospital deaths. Patients who died had higher NIHSS, were older, had lower GFR, higher hs-CRP and lower albumin. With univariate analysis association between in-hospital mortality and NIHSS, GFR, total cholesterol and LDL cholesterol was found. With Cox multivariable regression analysis of risk factors, NIHSS, GFR, total cholesterol and LDL cholesterol were only predictors of in-hospital mortality.
COBISS.SI-ID: 2860095
Cardio/cerebrovascular complications are the leading cause of morbidity and mortality in patients with end-stage renal disease. The excess cardio/cerebro-vascular risk and mortality are present already in patients with earlier stages of chronic kidney disease. Furthermore, renal insufficiency is also known as a strong independent predictor of mortality in patients with known cardio/cerebro-vascular diseases and also in patients with peripheral artery disease. Authors present different studies published in this field and also add some their own results.
COBISS.SI-ID: 3315519
Authors present association between cardio/cerebrovascular disease and chronic kidney disease (CKD). Later their own results in patients with stroke and CKD are presented. The most important results: patients with CKD and stroke have higher values of some risk factors (homocistein, CRP), lower values of total and LDL cholesterol and albumin. CKD influences NIHSS at admission and dismission. CKD has impact on mortality.
COBISS.SI-ID: 2791487
Chronic kidney disease (CKD) is frequent in patients with stroke. Patients with CKD are older, women are more frequent. Patients with CKD and stroke have higher values of some risk factors (homocistein, CRP), the role of dyslipidemia is not clear. In our study we found in these patiens lower values of total and LDL cholesterol and albumin suggesting association between atherosclerosis and malnutrition. CKD influences on NIHSS and has impact on mortality. Cystatin C is better marker than creatinine in predicting mortality in these patients.
COBISS.SI-ID: 3585343