To better understand the ecology and epidemiology of the highly pathogenic avian influenza virus in its transcontinental spread, we sequenced and analyzed the complete genomes of 36 recent influenza A (H5N1) viruses collected from birds in Europe, northern Africa, and southeastern Asia. These sequences, among the first complete genomes of influenza (H5N1) viruses outside Asia, clearly depict the lineages now infecting wild and domestic birds in Europe and Africa and show the relationships among these isolates and other strains affecting both birds and humans.
COBISS.SI-ID: 2773370
Rotaviral RNA was detected in the stool sample of an asymptomatic fattening pig at a Slovenian pig farm. To characterize the rotavirus, RT-PCR was used for the VP7, VP4 and NSP4 genes. Sequencing reaction was performed for the molecular analysis of amplified genes. Phylogenetic and molecular analysis of the VP7 antigen regions revealed the sample to be from a new lineage of G1 genotypeThis new rotavirus strain, named P21-5, differed greatly from all rotaviruses characterized so far in all three genes analyzed. The virulence of this strain is not clear yet and has to be investigated.
COBISS.SI-ID: 2710138
We describe the first transmission of Mycobacterium tuberculosis from human to cattle confirmed by molecular typing of isolates involved in the transmission. Although indirect data, suggesting that the humans suffering from active TB are the most probable source of M. tuberculosis in cattle, have been described before we consider this report as the first unequivocal evidence of human-to-cattle transmission of M. tuberculosis. Namely, we were able to confirm molecularly the epidemiological relatedness of the strains infecting the human and cattle involved in the transmission.
COBISS.SI-ID: 2324858
We evaluated time profile excretion of doramectin (DOR) in blood plasma and milk after pour-one application performed in autohtone Istrian Pramenka sheep. Mean elimination half-lives (t1/2) of DOR it was longer than in other avermectins. We observed the higer amount of DOR excreted in milk and ingested by suckling lambs. The results contributed to understanding of the persistence and excretion patterns in lactating sheep.
COBISS.SI-ID: 2237050
Doctoral thesis is based on 5 original scientific papers published in journals with high impact factor. General introduction is followed by description of analytical method used for detection of avermectins in feces and soil, which enabled to monitor the process of dissipation of avermectins in feces and soil under different experimental conditions. The thesis ends with the presentation of ecotoxicological data and general discussion. The thesis presents original world-class scientific work with the new insights into ecotoxicology and into the fate of veterinary medicines in the environment.
COBISS.SI-ID: 2747002