The motivation for the book Fate and effects of the residues of anticancer drugs in the environment ki jo je izdala založba Springer Nature Switzerland was the desire to bring together current knowledge and research on the presence and effects of cytostatic drug residues in the aqueous environment. The book contains 18 chapters and represents the combined work of leading scientists from different research institutions from across the globe. It covers all relevant aspects of the presence of cytostatic drug residues in wastewaters and natural aquatic systems, where numerous analogies are made between their pharmacokinetics and pharmacodynamics in humans and their effects on the environment.
C.01 Editorial board of a foreign/international collection of papers/book
COBISS.SI-ID: 33112359The doctoral thesis of Matjaž Novak was focused on determining the harmful effects of residues of cytostatic drugs in the environment on aquatic organisms and humans. He studied the toxic and genotoxic potential of selected cytostatics in fish and human cell models in vitro and in the zebrafish model using an innovative approach, combining toxicological methodologies with toxicogenomic analyzes. This provided insight into the molecular pathways of formation and consequences of adverse effects and the prediction of the effects of long-term exposure to low, environmentally relevant concentrations. He showed that at these very low concentrations, some cytostatics cause adverse effects. The results of this dissertation are an important scientific achievement in the field of research into environmental pollutants and their harmful effects on the environment and human health. They provide guidelines for further research and legislative modernization of the management of residues of active pharmaceutical ingredients in the environment.
D.09 Tutoring for postgraduate students
COBISS.SI-ID: 293862144