Photobiomodulation (PBM) therapy of salivary glands with polychromatic polarised light or with LED light positively affects caries risk factors in high caries risk patients therefore increases the chance to avoid new caries lesion formation. It can be considered as useful supporting method in treatment and preventive strategies for high caries risk patients. In causative therapy of caries, PBM could not substitute the gold standard. PBM addresses to one of the major risk factors, which gold standard of caries management cannot - saliva quality and its secretion. Our findings and research are directed to patients with dry mouth syndrome, who would mostly benefit from PBM as a supplementary or a preventive measure to help in decreasing caries risk.
B.04 Guest lecture
COBISS.SI-ID: 3328891The periodontal tissues anchored teeth to the jaw. They consist of gingiva, root cementum and alveolar bone. Healthy gingiva is colar pink and fulfils the interdental spaces. Due to the accumulation of dental plaque (biofilm), the gingiva become inflamed, red and swollen, and shows tendency to bleeding. With the progression of inflammation, destruction of other periodontal tissues occur, periodontal pockets are formed around the teeth, gingival recession are recognised, mobility of teeth increased, and finally the teeth could be lost. The disease is very widespread in Slovenia and is progressing with age. Inflammation of periodontal tissues is a chronic disease through the ulcerated wound of periodontal pockets the bacteria and inflammatory mediators enter the bloodstream, which damage the distant organs. In order to prevent periodontal disease, it is important carefully remove dental plaque daily from all dental surfaces and regularly visit a dentist.
F.17 Transfer of existing technologies, know-how, methods and procedures into practice
COBISS.SI-ID: 32962343The purpose of this study was to determine the prevalence of musculoskeletal disorders, the areas of pain and the risk factors for the development of musculoskeletal disorders in dental practitioners, dental assistants and technicians in Slovenia. The research sample consisted of 90 randomly selected dental workers, including general dentists, dental specialists, dental assistants and dental technicians. The total of 79.8% dental workers presented with at least one musculoskeletal complaint. The musculoskeletal pain most frequently occurs in the neck (60.71%), upper back (52.38%), right shoulder (44.04%), lower back (41.66%), hips/buttocks (29.76%) and the right wrist (23.81%). The findings of this study indicate that most dental workers suffer from musculoskeletal disorders. The prevalence of musculoskeletal disorders among dental workers could be reduced by ergonomic working environment, regular breaks, maintenance of good overall health, and the performance of exercises designed to prevent the risk factors specific to dental workers.
F.17 Transfer of existing technologies, know-how, methods and procedures into practice
COBISS.SI-ID: 6290348Purpose: to determine a detailed clinical and haplotypic variability of the Slovenian USH2A patients with homozygous c.11864G)A (p.Trp3955Ter) nonsense mutation and to develop sensitive, accurate and rapid screening test. Methods: Ten unrelated homozygous patients with detailed ophthalmological exam were included in our study. The High-Resolution Melting (HRM) method was developed for fast and reliable detection of the c.11864G)A mutation. Results: The c.11864G)A mutation represents the vast majority of pathogenic alleles in Slovenian USH2A-Usher syndrome population (84%). The median age of onset of nyctalopia was 16 years and all patients younger than 40 years had hyperautofluorescent rings on fundus autofluorescence imaging. The Kaplan Meier survival analysis showed a decline of central vision after the age of 40, with 50% patients reaching visual acuity (VA) (- 0.05 at the average age of 66 years visual field diameter less than 20° at the average age of 59 years. There was a relatively large phenotypic variability in the retinal and audiological phenotype. Analysis of the p.Trp3955Ter-homozygous patients revealed four different haplotypes, with the frequency of the most common haplotype ~65%. Disease severity did not correlate with the haplotype. Conclusions: According to the natural history of homozygous p.Trp3955Ter patients any therapy aimed to slow disease progression in these patients would be best started before the age of 40. Phenotypic variability...
F.17 Transfer of existing technologies, know-how, methods and procedures into practice
COBISS.SI-ID: 34616281USH2A mutation is the most common cause of retinitis pigmentosa, with or without hearing impairment. Patients most commonly exhibit hyperautofluorescent ring on fundus autofluorescence imaging (FAF) and rod-cone dystrophy on electrophysiology. A detailed study of three USH2A patients with a rare pattern of double hyperautofluorescent rings was performed. Twenty-four patients with typical single hyperautofluorescent rings were used for comparison of the ages of onset, visual fields, optical coherence tomography, electrophysiology, and audiograms. Double rings delineated the area of pericentral retinal degeneration in all cases. Two patients exhibited rod-cone dystrophy, whereas the third had a cone-rod dystrophy type of dysfunction on electrophysiology. There was minimal progression on follow-up in all three. Patients with double rings had significantly better visual acuity, cone function, and auditory performance than the single ring group. Double rings were associated with combinations of null and missense mutations, none of the latter found in the single ring patients. According to these findings, the double hyperautofluorescent rings indicate a mild subtype of USH2A disease, characterized by pericentral retinal degeneration, mild to moderate hearing loss, and either a rod-cone or cone-rod pattern on electrophysiology, the latter expanding the known clinical spectrum of USH2A-retinopathy.
F.17 Transfer of existing technologies, know-how, methods and procedures into practice
COBISS.SI-ID: 34598361