In this paper the biological response to various TiO2 nanostructured morphologies after gaseous plasma treatment was studied. The usefulness of nanostructured surfaces for implantable materials has already been acknowledged, while less is known on the combined effect of nanostructured plasma modified surfaces. In the present work the influence of oxygen plasma treatment on nanostructured titanium oxide (TiO2) was shown to enhance osteoblast-like cell response.
COBISS.SI-ID: 29490727
Sterilization is the final surface treatment procedure of all implantable devices and is one of the key factors which have to be considered before implementation. Since different sterilization procedures for all implantable devices influence mechanical properties as well as biological response, the influence of different sterilization techniques on titanium nanotubes was studied. Commonly used sterilization techniques such as autoclaving, ultra-violet light sterilization, hydrogen peroxide plasma sterilization and non- commercial oxygen plasma were studied. It was observed that autoclave sterilization resulted in destruction of nanotubular features, while UV-light and both kinds of plasma sterilization did not cause any significant morphological changes on the surfaces.
COBISS.SI-ID: 29305383
Surface charge is one of the most significant properties for the characterisation of a biomaterial, being a key parameter in the interaction of the body implant with the surrounding living tissues. The present study concerns the systematic assessment of the surface charge of electrochemically anodized TiO2 nanotubular surfaces. The results showed that all the surfaces were negatively charged at physiological pH. However, the zeta potential values were dependent on the electrolytic conditions and on the surface characteristics. Results contribute to enrich the state-of-art on the characterisation of nanostructured implant surfaces at the bio-interface.
COBISS.SI-ID: 29777447