We presented the development of a web-based treatment planning application for electrochemotherapy and irreversible electroporation at the 6th computational surgery conference in Bordeaux, France. The components of the underlying electric field and temperature model are presented. The different approaches for evaluating treatment planning are discussed. Finally, the possible steps towards validation of the models are presented: validation with measured currents and voltages and validation using medical images.
F.18 Transfer of new know-how to direct users (seminars, fora, conferences)
Course attendees learned the basic methods of numerical modelling for treatment planning of electrochemotherapy and irreversible electroporation using the finite element method. The course covered building the model geometry, setting the material properties and boundary conditions, computing the electric field strength and manually optimizing the coverage of the target region with electric fields.
F.18 Transfer of new know-how to direct users (seminars, fora, conferences)
COBISS.SI-ID: 11634004Course attendees leaned the basics of using the finite element method to determine tissue heating during the application of electric pulses for irreversible electroporation. The basics of heat transfer in biological tissue and calculation of thermal damage due to exposure to elevated temperatures were demonstrated. The use of Arrhenius integral for evaluation of thermal damage was presented.
F.18 Transfer of new know-how to direct users (seminars, fora, conferences)
COBISS.SI-ID: 11634260