Projects / Programmes
Mechanisms of central neuromuscular fatigue in human
| Code |
Science |
Field |
Subfield |
| 3.03.00 |
Medical sciences |
Neurobiology |
|
| Code |
Science |
Field |
| B640 |
Biomedical sciences |
Neurology, neuropsychology, neurophysiology |
| H361 |
Humanities |
Neurolinguistics |
human, motor control, neuromuscular fatigue, electrophysiology
Researchers (2)
| no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
| 1. |
21495 |
PhD Nejc Šarabon |
Sport |
Researcher |
2005 - 2007 |
0 |
| 2. |
00341 |
PhD Jože Trontelj |
Neurobiology |
Head |
2005 - 2007 |
0 |
Organisations (1)
Abstract
The goal of the proposed research is to describe basic principles of muscle co-activation patterns that appear as an accompanying compensational mechanism of the neuromuscular system during fatiguing single joint isometric motor task. We aim to illuminate neurobiological mechanisms of central fatigue behind such motor behaviour and to develop diagnostic procedures for routine use.
We hypothesise that (i) there is a functional relationship between the level of fatigue and co-activation of the neighbouring muscles, (ii) drop of the voluntary muscle force and related co-activations is mirrored by the changes in the central nervous system excitability, (iii) patterns of the motor behaviour and its control depend on the initial state of the central system, (iv) it is possible to affect mechanisms of central fatigue using manipulations of different sensory subsystems, which are known to have potentiating and/or inhibitory effects.
The above hypothesis are going to be tested using the disposable electrophysiological equipment, which will be used to monitor inter-muscular coordination, evoked muscle potentials (m M wave, H wave, MEP) and muscle force, and for the purpose of the sensory conditioning.
Respecting principles of the medical ethics and Helsinki declaration, adult healthy subjects will be recruited into the study.
