Filters
cris logo
-
New search Filters
Select from list
Displayed from Show more
You have reached the maximum number of displayed search results.
All results displayed
No results are available for the search performed
Displayed from
You have reached the maximum number of displayed search results.
All results displayed
Loading results
Obtaining statistical data

Projects / Programmes source: ARIS

Synthesis of heterocyclic analogs of amino acids and peptides

Edit
Research activity

Code Science Field Subfield
1.04.00  Natural sciences and mathematics  Chemistry   

Code Science Field
P003  Natural sciences and mathematics  Chemistry 
P390  Natural sciences and mathematics  Organic chemistry 
P395  Natural sciences and mathematics  Organometallic chemistry 
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (14)
no. Code Name and surname Research area Role Period No. of publications
1.  23491  PhD David Bevk  Pharmacy  Junior researcher  2004 - 2007  0 
2.  19281  PhD Zdenko Časar  Chemistry  Researcher  2004  0 
3.  22602  PhD Uroš Grošelj  Chemistry  Researcher  2004 - 2007  0 
4.  17140  Tončka Kozamernik-Hudeček    Technical associate  2004 - 2007  0 
5.  20062  PhD Renata Osolnik  Chemistry  Researcher  2005 - 2007  0 
6.  26549  PhD Lidija Pezdirc  Chemistry  Junior researcher  2006 - 2007  0 
7.  21341  PhD Samo Pirc  Chemistry  Researcher  2004  0 
8.  18316  PhD Lovro Selič  Chemistry  Researcher  2004 - 2007  0 
9.  00868  PhD Branko Stanovnik  Chemistry  Head  2004 - 2007  6 
10.  08284  PhD Jurij Svete  Chemistry  Researcher  2004 - 2007  0 
11.  17142  Tatjana Toporiš Stipanovič    Technical associate  2004 - 2007  0 
12.  25443  PhD Uroš Uršič  Chemistry  Junior researcher  2005 - 2007  0 
13.  26548  PhD Jernej Wagger  Chemistry  Junior researcher  2006 - 2007  0 
14.  15761  PhD Silvo Zupančič  Pharmacy  Researcher  2004 - 2007  0 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0103  University of Ljubljana, Faculty of Chemistry and Chemical Technology  Ljubljana  1626990  10 
Abstract
Functionalised heterocyclic compounds containing an amino acid or a peptide structural element represent an important group of organic compounds (peptidomimetics) with potential biological activity. Witihin the frame of the proposed research project, novel reagents and synthetic methodologies for the preparation of heterocyclic analogs of amino acids and peptides, as well as related functionalised heterocyclic compounds, will be developped. The main issues of this research project are: a) development of new general synthetic methodologies and new reagents, which would enable selective preparation of diverse types of peptidomimetics (selectivity and diversity oriented synthesis) b) stereochemical studies directed towards development of stereoselective synthetic methods c) application of new reagents and new synthetic methosdologies in parallel and combinatorial synthesis. Within the frame of the above mentioned general research orientation, the following topics will be studied: a) preparation and synthetic applications of new chiral enaminones in the synthesis of optically active heteroarylalanines and related compounds, synthesis of heterocyclic systems with incorporated amino acid structural element, and synthesis of natural product analogs b) study on reactivity of enaminones towards organometallic reagents followed by applications in the synthesis of dehydroalanines, analogs of aplysinopsins, and related compounds c) study on regio- and stereoselective 1,3-dipolar cycloadditions 3-pyrazolidinone-1-azomethine imines leading to 2-amino-1-oxopyrazolo(1,2-a)pyrazole-7-carboxylates as heterocyclic analogs of dipeptides e) applications of new synthetic methods and new reagents in solid-phase synthesis of functionalised heterocycles.
Confirmation required
Views history
Favourite