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Projects / Programmes source: ARIS

THE ROLE OF CARDIOVASCULAR RISK FACTORS IN DIALYSIS PATIENTS

Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   

Code Science Field
B530  Biomedical sciences  Cardiovascular system 
Keywords
end stage renal failure, hypertension, atherosclerosis, left venticular hypertrophy, anemia, dyslipidemia, microinflammation
Evaluation (rules)
source: COBISS
Researchers (4)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  07616  MSc Maksimiljan Gorenjak  Human reproduction  Researcher  2003 - 2004 
2.  15751  PhD Radovan Hojs  Metabolic and hormonal disorders  Head  2003 - 2004 
3.  02053  PhD Ivan Krajnc  Microbiology and immunology  Researcher  2003 - 2004 
4.  15750  PhD Artur Pahor  Microbiology and immunology  Researcher  2003 - 2004 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0334  University Medical Centre Maribor  Maribor  5054150000 
Abstract
Cardiovascular disease (CVD) is the main cause of morbidity and mortality in patients with end stage renal failure (ESRD) on dialysis. CVD morbidity is approximately 10-20 times higher in patients with ESRD compared with that in the general population, but in young dialysis patients between 25 and 34 years is annual mortality from CVD up to 1000 times higher than in the general population. This project is prospective research, which will define the role of hypertension, one of the main risk factors for CVD in dialysis patients. In study, we will define association between interdialytic values of blood pressure and mortality, particularly which values of blood presssure between two dialytic procedures or during dialysis and/or 24 or 48 hours measurement of blood pressure are most associated with morbidity and mortality of dialysis patients. We will also define frequence and stage of left ventricular hypertrophy (LVH), which is good predictor for CVD and association between LVH and hypertension, anemia, dyslipidemia, homocystein and secundary hyperparathyroidism. We will also define the role of microinflammation, that plays important role in the process of atherosclerosis.We will also make complete ophtalmological examination in all dialysis patients. This research is intented to define the risk factors for CVD in dialysis patients, which influence on survivor and quality of life of this patients.
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